Top 10 Things to Do in Santa Cruz de la Sierra, Bolivia: Culture, Charm & City Secrets
- Natalija Ugrina
- 3 days ago
- 8 min read
When most travelers picture Bolivia, they imagine llamas in the Andes, salt flats in Uyuni, or the colonial charm of Sucre. But on my recent trip, I discovered a completely different side of the country: Santa Cruz de la Sierra—a tropical, culturally rich city that’s often overlooked.
Located in Bolivia’s eastern lowlands, Santa Cruz de la Sierra is the country's largest and fastest-growing city. It's warm year-round, has a laid-back vibe, and is full of unexpected gems. I stayed within the city limits for my visit—and honestly, I found more than enough to keep me fascinated.
So if you’re planning your trip and wondering about the top things to do in Santa Cruz de la Sierra Bolivia, this blog is for you. Here's everything I explored, loved, and absolutely recommend.
1. Climb the Cathedral Bell Tower
Right in the heart of the historic center, Basílica Menor de San Lorenzo—better known as the Santa Cruz Cathedral—is one of the city’s most iconic landmarks and the perfect starting point for your adventure. Located on Plaza 24 de Septiembre, this neoclassical cathedral with twin towers dates back to the 1600s, though it was rebuilt in the early 20th century after several structural changes.
The interior is grand yet serene, with soaring ceilings, colorful stained-glass windows, and intricately carved woodwork that reflects both Spanish and local influence. Don’t miss the small cathedral museum tucked inside—it holds religious artifacts, colonial-era artwork, and some fascinating documents related to the Catholic Church’s role in the city’s development.
But the real magic? Climbing the bell tower. A narrow, winding staircase leads you up to panoramic views over the historic center of Santa Cruz. From the top, you’ll spot red-tiled roofs, leafy plazas, and the spires of neighboring churches—an incredible contrast to the modern skyline in the distance.
I went just before sunset and the light was dreamy. It’s peaceful, historic, and honestly one of the best things to do in Santa Cruz de la Sierra Bolivia—especially if you’re a sucker for views and a bit of quiet reflection.
2. Visit the Museo de la Independencia
A few steps from the plaza, this small museum gives you a meaningful glimpse into Bolivia’s fight for independence and Santa Cruz’s role in it. Housed in a colonial building with creaky floors and historical artifacts, the Museo de la Independencia is intimate and educational.
If you love learning about the places you visit, this is one of the best things to do in Santa Cruz de la Sierra Bolivia for a dose of history.
3. Stand at the Heart of South America Monument
Yes, Santa Cruz proudly claims to be the geographic heart of South America, and there’s a giant metal sculpture marking the spot! Located in a busy roundabout, the Corazón de América del Sur monument is a fun and quirky stop.
It’s symbolic more than scientific, but I still couldn’t resist taking a photo there—it’s not every day you stand at the “center” of a continent!
4. Discover Manzana Uno – A Contemporary Art Space in the Heart of the City
If you're looking for something a little unexpected while exploring Santa Cruz de la Sierra, make time for Manzana Uno Espacio de Arte. Tucked just a block from Plaza 24 de Septiembre, this vibrant open-air cultural center showcases contemporary art in a space that’s equal parts gallery and city square.
I stumbled across it while walking between museums and was instantly drawn in by the murals and sculptures that line the courtyard. The exhibitions change regularly and feature everything from political commentary and social justice themes to abstract installations and photography. It’s a great reminder that Santa Cruz isn’t just about colonial history—it’s also a city full of creative voices and modern perspectives.
Admission is free, and there’s usually something going on: art talks, local workshops, or cultural festivals. Whether you’re an art lover or just want to take a quiet, inspiring break during your city stroll, this spot definitely deserves a place on your list of things to do in Santa Cruz de la Sierra Bolivia.
5. Admire Colonial Beauty at Museo de la Ciudad Altillo Beni
Right in the center of the city, the Museo de la Ciudad Altillo Beni is housed in one of Santa Cruz de la Sierra’s most iconic colonial mansions. Known locally as El Altillo Beni, the building dates back to the 19th century and is a gorgeous example of traditional Cruceño architecture. You’ll immediately notice the carved wooden columns, clay tile roof, and the upper-level balconies with balustrades that overlook the street—once used to watch parades and local games like la sortija.
Inside, the museum offers a thoughtful look at Santa Cruz’s past, with exhibits covering everything from the city’s early development to political and cultural milestones. The rooms are filled with artifacts, documents, and artwork that help paint a picture of how the city evolved over time. There’s also a rotating schedule of temporary exhibitions and cultural events, so there’s always something new to see.
I found myself lingering longer than expected—every corner had something that made me pause. If you love historic architecture with a story to tell, this spot should definitely be on your list of things to do in Santa Cruz de la Sierra Bolivia.
6. Discover Museo Melchor Pinto Parada
Located just a few blocks from the main plaza, the Museo Melchor Pinto Parada offers a fascinating glimpse into the cultural and intellectual legacy of Santa Cruz de la Sierra. Named after Dr. Melchor Pinto Parada, a respected physician, civic activist, and public health pioneer, the museum is dedicated to preserving both his memory and the broader history of the city.
Dr. Pinto Parada is widely remembered for his efforts in modernizing Santa Cruz during the 20th century—especially through his advocacy for regional autonomy, healthcare access, and education. His influence shaped much of the city’s civic development and cultural identity.
The museum is set in his former home, a beautiful colonial-style house filled with period furnishings, historical photographs, and personal artifacts. Each room tells a story—from Santa Cruz’s medical past to its political movements and literary traditions. I especially enjoyed seeing how personal and authentic the space felt, almost like stepping into a preserved moment in time.
It’s one of those lesser-known spots that really adds depth to your understanding of the city—and a must-visit for history lovers exploring Santa Cruz de la Sierra Bolivia.
7. Explore Casa de la Cultura
The Casa de la Cultura Raúl Otero Reiche is a cultural hub hosting exhibitions, concerts, and literary events. Even if there’s no event happening when you visit, the building’s colonial-style architecture and peaceful courtyard make it a lovely place to stop by.
It’s right in the historic center, so it’s an easy addition to your walking route through the city.
8. Dine at El Aljibe
One of the best meals I had in Santa Cruz was at El Aljibe, a charming restaurant in a restored colonial home. They serve traditional Cruceño cuisine like majadito, locro, and sopa tapada in a beautiful garden setting.
I ordered the majadito de charque with a fresh passionfruit juice and loved every bite. It’s one of the top places to eat in the city—and a must for anyone wanting an authentic Bolivian dining experience.
9. Unwind at Plaza 24 de Septiembre
You’ll naturally pass through this central plaza more than once—it’s the heartbeat of the city. Lush with palms and surrounded by cafes and colonial buildings, Plaza 24 de Septiembre is the perfect place to take a break.
Grab a coffee, sit on a bench, and soak in the sights: musicians, vendors, lovers walking hand in hand, and locals watching the day go by.
10. Spot Hidden Art and Sculptures Around Town
Santa Cruz isn’t flashy, but if you look closely, you’ll find artistic details everywhere—murals, quirky statues, and surprising sculptures tucked into corners. Walk through Equipetrol and the city center with an eye for detail and you'll spot them.
These little surprises gave me such a sense of place and creativity that I didn't expect to find in such a fast-growing city.
🏛️ Bonus Stop: Snap a Photo at the Gobernación Building
Right next to Plaza 24 de Septiembre, the Gobierno Autónomo Departamental de Santa Cruz building makes for a perfect quick photo stop. Draped in the colors of the Bolivian and Santa Cruz flags and surrounded by towering palms, it’s one of the most photogenic government buildings in the city. I couldn’t resist taking a moment here between museum visits.
🏨 Where to Stay in Santa Cruz de la Sierra
Whether you're traveling on a budget or looking to splurge, Santa Cruz de la Sierra has great options for every type of traveler. Below are three standout hotels I recommend based on location and amenities—and yes, the links below are affiliate links, which means I may earn a small commission at no extra cost to you if you book through them. Thank you for supporting my blog!
💎 Marriott Santa Cruz de la Sierra Hotel (Luxury)
Located in upscale Equipetrol, this modern hotel features panoramic city views, a rooftop pool, and sleek, comfortable rooms.Ideal for: Travelers seeking luxury, comfort, and top-notch amenities.
💼 Hotel Cortez (Mid-range)
A beautiful blend of tropical greenery and Bolivian hospitality, Hotel Cortez is centrally located with a relaxing pool area and lovely gardens.Ideal for: Couples, solo travelers, and business travelers who want comfort without going over budget.
💸 Senses Centro Hotel (Budget)
Right on Plaza 24 de Septiembre, this is a great budget option with rooftop views and unbeatable access to Santa Cruz’s main attractions.Ideal for: Budget-conscious travelers who still want convenience and charm.
🍴 Best Places to Eat: Top Things to Do in Santa Cruz de la Sierra Bolivia
Here are my favorite restaurants and cafés from the trip—each one memorable in its own way:
🫕 El Aljibe
Traditional Bolivian food in a dreamy garden setting. Don’t miss the majadito!
🧀 Chalet La Suisse
For cheesy comfort food and Swiss classics like fondue and rösti. Cozy and delicious.
🌸 Jardín de Asia
High-end fusion dining that blends Asian and Bolivian flavors. Elegant and creative.
🪴 Botánica
Plant-based bowls, smoothies, and healthy brunch in a light-filled, Instagram-friendly café.
✈️ Aviator
Chic bistro with aviation-themed decor, perfect for dinner or a stylish cocktail night.
🌴 Final Thoughts
Santa Cruz de la Sierra isn’t the Bolivia you see on postcards—but that’s exactly why you should visit. It’s warm, creative, energetic, and full of history and flavor. I only scratched the surface staying inside the city, but I found so many beautiful moments—climbing bell towers, sipping coffee in leafy plazas, and learning about a side of Bolivia most people skip.
So if you’re planning a trip, don’t rush through. Stay a while, wander on foot, eat something new, and let the unexpected charm of Santa Cruz take you by surprise.
👉 Curious about other lesser-known cities in South America? Don’t miss my post on Underrated Capitals of South America You Need to Visit Before Everyone Else for more hidden gems like this one.
Planning your trip? Drop your questions in the comments or tell me your favorite place if you’ve been! And for more off-the-radar travel inspiration, check out my other blog posts at:👉 www.natalijaugrina.com/blog